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  • 标题:A Bayesian Semiparametric Temporally-Stratified Proportional Hazards Model with Spatial Frailties
  • 本地全文:下载
  • 作者:Timothy E. Hanson ; Alejandro Jara ; Luping Zhao
  • 期刊名称:Bayesian Analysis
  • 印刷版ISSN:1931-6690
  • 电子版ISSN:1936-0975
  • 出版年度:2012
  • 卷号:07
  • 期号:01
  • DOI:10.1214/12-BA705
  • 出版社:International Society for Bayesian Analysis
  • 摘要:

    Incorporating temporal and spatial variation could potentially enhance
    information gathered from survival data. This paper proposes a Bayesian semi-
    parametric model for capturing spatio{temporal heterogeneity within the propor-
    tional hazards framework. The spatial correlation is introduced in the form of
    county{level frailties. The temporal e®ect is introduced by considering the strati-
    ¯cation of the proportional hazards model, where the time{dependent hazards are
    indirectly modeled using a probability model for related probability distributions.
    With this aim, an autoregressive dependent tailfree process is introduced. The
    full Kullback{Leibler support of the proposed process is provided. The approach
    is illustrated using simulated data and data from the Surveillance Epidemiology
    and End Results database of the National Cancer Institute on patients in Iowa
    diagnosed with breast cancer.

  • 关键词:Spatio{temporal modeling; Dependent processes; Tailfree processes; Breast cancer
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