摘要：Problem statement: Healthcare-associated infections are the 5th leading cause of death in the United States. Catheter-Related Bloodstream Infections (CRBSIs) comprise 14% of all healthcare-associated infections and contribute to increased mortality and financial costs. Antimicrobial-impregnated sponge discs to be used surrounding the catheter insertion site are a newer addition to the options available for the prevention of catheter-related infections. Approach: This review critically appraises the literature regarding the utility of antimicrobial-impregnated discs. We performed a literature search using the MEDLINE (1948-November 2011) database. Only controlled clinical trials were included and the electronic database search was performed using the following MeSH and keyword search terms: (
关键词：Catheter-Related Bloodstream Infections (CRBSIs); United States (US); Polyhexamethylene Biguanide (PHMB); Coagulase-Negative Staphylococcus (CoNS); Central Venous Catheters (CVCs); National Institutes of Health (NIH)
