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  • 标题:Neuroendocrine tumor of the skin of head and neck
  • 本地全文:下载
  • 作者:Stošić Srboljub ; Đurđević Dejan ; Kozomara Ružica
  • 期刊名称:Vojnosanitetski pregled
  • 印刷版ISSN:0042-8450
  • 出版年度:2005
  • 卷号:62
  • 期号:11
  • 页码:861-864
  • DOI:10.2298/VSP0511861S
  • 出版社:Military Medical Academy, INI
  • 摘要:

    Background. Merkel cell carcinom is a rare neuroendrocine tumor of skin which manifests it self through aggressive growth and early regional metastasis. It develops mainly in older population. Locally, the tumor spreads intracutaneously. Case report. We showed two cases (females of 89 and 70 years old) hospitalized within the last two years. The first patient was treated surgically three times. After the surgery, the patient was treated with radio therapy, and died 3 years from the beginning of the treatment. The second patient with this neuroendocrine tumor with the high malignancy potential and huge regional metastasis, was treated surgically, and died a month and a half after the operation. Conclusion. These two cases confirmed the aggressive and recidivant growth of this tumor with the difficult pathologic investigation, and the extremely bad prognosis inspite of the treatment.

  • 关键词:carcinoma; Merkel cell; head and neck; neoplasms; neuroendocrine tumors; skin neoplasms; diagnosis; immunohistochemistry; prognosis; treatmentoutcome; aged
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