首页    期刊浏览 2024年11月25日 星期一
登录注册

文章基本信息

  • 标题:Agranulocytosis induced by metamizole and its management with granulocyte growth factor
  • 本地全文:下载
  • 作者:Čeleketić Dušica ; Trpković Andreja ; Cvetković Zorica
  • 期刊名称:Vojnosanitetski pregled
  • 印刷版ISSN:0042-8450
  • 出版年度:2005
  • 卷号:62
  • 期号:1
  • 页码:79-82
  • DOI:10.2298/VSP0501079C
  • 出版社:Military Medical Academy, INI
  • 摘要:

    Drug-induced agranulocytosis was defined as a severe selective neutropenia caused by an unexpected drug reaction. Metamizole was the most common nonopioid analgesic drug associated with agranulocytosis. It was also associated with combined blood dyscrasias and other severe immunologic disorders. The risk of agranulocytosis by metamizole seemed to be considerably higher than estimated formerly. Modern management with broad-spectrum antibiotics and haematopoietic growth factors reduced the mortality in those patients. Two cases of agranulocytosis caused by metamizole were reported.

  • 关键词:agranulocytosis; dipyrone; granulocyte colony-stimulating factor
国家哲学社会科学文献中心版权所有