The RIASEC structure has been tested in Croatian and Serbian sample. The Holland's Self-directed Search was applied on a sample of 746 high-school pupils (384 coming from Croatia and 362 from Serbia). The adequacy of hexagonal model has been analyzed with Hubert and Arabie's randomization test, Myors' test and Multidimensional scaling procedure. Although the analyses have shown somewhat different results, generally the similar fit of the hexagonal model to both samples was found. The theoretical two-dimensional underlying solution was tested with principal components analysis and in both samples two very similar underlying dimensions were found. Thus, the RIASEC structure in Croatia and Serbia was found to be very similar, both with respect to the hexagonal structure and the underlying dimensions. .