The two processes that, basically since the emergence of the classic civilizations, determine major changes in the basic spatial structures in the world are, de facto, of antipode basic characteristics (globalization and regionalisation), but it is often the case that there are elements with traits of complementarily. They have crucial effect on development and integration of geo-spaces and many research results indicate that, depending of the stage of the development, both processes were present in the geo-space in various forms in almost all the phases of its development and that they have contributed to establishment of all the new spatial-structural relations. The subject of this analyses is, among other issues, a brief genesis of these two processes, including identification of their main starters and effects. Besides from that, there is a special attention paid to the role of the traffic as their basic element and one of the important initiators and its role in those parts of the European continent that are not yet included by these processes of crucial changes of the geo-space as the whole.