Water regime and water balance of the Đetinja River were analysed in this paper on the basis of a thirty-year data series on water level and discharge in the period from 1978 to 2008. The analysis of the Đetinja water level showed the mean annual water level of 53 cm in the mentioned period, whereas the lowest mean monthly water levels were in August, and the maximum mean monthly water levels in March and April. The average mean annual discharge of the Đetinja near Šengolj was 5.60 m3/s of the observation period 1978-2008. The annual value of the average discharges was similar to the annual value of the mean monthly low and high waters. It has been concluded that the Đetinja River belongs to the moderate-continental variance of the pluvial-nival regime. The results of the research have shown that about 5.60 m3/s of water is formed in the Đetinja Basin with specific runoff of 10.95 l/s/km2. Even though precipitation is not so low and ranges around 875 mm per year, the amount of the river inflow is smaller due to high evaporation of over 60%. Considering that the Šengolj hydrological station has been situated at 8.2 km from the mouth, and the station Stapari stopped working in 2002, there is an opinion that it would be significant to put the hydrological station in the part of the river course, as well as on larger tributaries. .