This paper deals with the historical approach to the study of disability, and attempts of its use in explaining the modern trends that determine the position of people with disability in society. Historical approach, through monitoring the chronological position of persons with disability, from ancient times until the present day, suggests the complexity of status of these persons in society, and their constant discrimination. The position of these people in modern society is significantly changed, but still, in addition to transparent right to equality, one can hardly speak of substantial equality. The essential equality would imply greater inclusion of persons with disability themselves, that began through the development of the social model of disability, as well as a multidisciplinary scientific approach to this problem.