期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2012
卷号：109
期号：40
页码：16046-16051
DOI：10.1073/pnas.1204479109
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Most chemiluminescence (CL) reactions usually generate only one-step CL, which is rarely dependent on the highly reactive and biologically/environmentally important hydroxyl radicals ([bullet]OH). Here, we show that an unprecedented two-step CL can be produced by the carcinogenic tetrachloro-1,4-benzoquinone (also known as p-chloranil) and H2O2, which was found to be well-correlated to and directly dependent on its two-step metal-independent production of [bullet]OH. We proposed that [bullet]OH-dependent formation of quinone-dioxetane and electronically excited carbonyl species might be responsible for this unusual two-step CL production by tetrachloro-1,4-benzoquinone/H2O2. This is a unique report of a previously undefined two-step CL-producing system that is dependent on intrinsically formed [bullet]OH. These findings may have potential applications in detecting and quantifying [bullet]OH and the ubiquitous polyhalogenated aromatic carcinogens, which may have broad biological and environmental implications for future research on these types of important species.
