摘要：This paper presents a novel mathematical model with multidrug-resistant (MDR) and
undetected TB cases. The theoretical analysis indicates that the disease-free equilibrium is
globally asymptotically stable if 𝑅0<1; otherwise, the system may exist a locally asymptotically
stable endemic equilibrium. The model is also used to simulate and predict TB epidemic
in Guangdong. The results imply that our model is in agreement with actual data and the
undetected rate plays vital role in the TB trend. Our model also implies that TB cannot be
eradicated from population if it continues to implement current TB control strategies.
