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  • 标题:Quantifying Optical Microangiography Images Obtained from a Spectral Domain Optical Coherence Tomography System
  • 本地全文:下载
  • 作者:Roberto Reif ; Jia Qin ; Lin An
  • 期刊名称:International Journal of Biomedical Imaging
  • 印刷版ISSN:1687-4188
  • 电子版ISSN:1687-4196
  • 出版年度:2012
  • 卷号:2012
  • DOI:10.1155/2012/509783
  • 出版社:Hindawi Publishing Corporation
  • 摘要:The blood vessel morphology is known to correlate with several diseases, such as cancer, and is important for describing several tissue physiological processes, like angiogenesis. Therefore, a quantitative method for characterizing the angiography obtained from medical images would have several clinical applications. Optical microangiography (OMAG) is a method for obtaining three-dimensional images of blood vessels within a volume of tissue. In this study we propose to quantify OMAG images obtained with a spectral domain optical coherence tomography system. A technique for determining three measureable parameters (the fractal dimension, the vessel length fraction, and the vessel area density) is proposed and validated. Finally, the repeatability for acquiring OMAG images is determined, and a new method for analyzing small areas from these images is proposed.
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