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  • 标题:Patient Specific Dosimetry Phantoms Using Multichannel LDDMM of the Whole Body
  • 本地全文:下载
  • 作者:Daniel J. Tward ; Can Ceritoglu ; Anthony Kolasny
  • 期刊名称:International Journal of Biomedical Imaging
  • 印刷版ISSN:1687-4188
  • 电子版ISSN:1687-4196
  • 出版年度:2011
  • 卷号:2011
  • DOI:10.1155/2011/481064
  • 出版社:Hindawi Publishing Corporation
  • 摘要:This paper describes an automated procedure for creating detailed patient-specific pediatric dosimetry phantoms from a small set of segmented organs in a child's CT scan. The algorithm involves full body mappings from adult template to pediatric images using multichannel large deformation diffeomorphic metric mapping (MC-LDDMM). The parallel implementation and performance of MC-LDDMM for this application is studied here for a sample of 4 pediatric patients, and from 1 to 24 processors. 93.84% of computation time is parallelized, and the efficiency of parallelization remains high until more than 8 processors are used. The performance of the algorithm was validated on a set of 24 male and 18 female pediatric patients. It was found to be accurate typically to within 1-2 voxels (2–4 mm) and robust across this large and variable data set.
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