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  • 标题:Predictors of Immunosuppressive Regulatory T Lymphocytes in Healthy Women
  • 本地全文:下载
  • 作者:Shalaka S. Hampras ; Mary Nesline ; Paul K. Wallace
  • 期刊名称:Journal of Cancer Epidemiology
  • 印刷版ISSN:1687-8558
  • 电子版ISSN:1687-8566
  • 出版年度:2012
  • 卷号:2012
  • DOI:10.1155/2012/191090
  • 出版社:Hindawi Publishing Corporation
  • 摘要:Immunosuppressive regulatory T (Treg) cells play an important role in antitumor immunity, self-tolerance, transplantation tolerance, and attenuation of allergic response. Higher proportion of Treg cells has been observed in peripheral blood of cancer cases compared to controls. Little is known about potential epidemiological predictors of Treg cell levels in healthy individuals. We conducted a cross-sectional study including 75 healthy women, between 20 and 80 years of age, who participated in the Data Bank and BioRepository (DBBR) program at Roswell Park Cancer Institute (RPCI), Buffalo, NY, USA. Peripheral blood levels of CD4
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