期刊名称：Advance Journal of Food Science and Technology
印刷版ISSN：2042-4868
电子版ISSN：2042-4876
出版年度：2012
卷号：4
期号：2
页码：91-96
出版社：MAXWELL Science Publication
摘要：The aim of the current study was to evaluate the iridoid content, as well as the in vitro and in vivo bioactivities, of a beverage containing noni fruit, Cornelian cherries, and olive leaf extract (Thrive Adaptogenics Max). The average total iridoid content of the beverage was 2.09 mg/mL. The major iridoids present were identified as asperulosidic acid, deacetylasperulosidic acid, oleuropein, morroniside, loganic acid, and loganin. In the 2, 2-Diphenylpicrylhydrazyl (DPPH) radical scavenging assay, remarkably high in vitro antioxidant activity was observed, with an IC50 of 3.8 :L/mL. In vivo bioactivities were evaluated in type 2 diabetic Sprague Dawley rats. In a dose-dependent manner, Thrive Adaptogenics Max reduced abnormal weight gain, blood glucose levels, and serum Advanced Glycation End products (AGEs), as well as improved immunity via increased T cell counts and CD4+/CD8+ ratios. These results suggest that this blend of ingredients is beneficial for improving and maintaining health in the general population, as well as among those with metabolic imbalance.
