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  • 标题:Absorbed dose uncertainty estimation for proton therapy
  • 本地全文:下载
  • 作者:Spasić-Jokić Vesna ; Dobrosavljević Aleksandar ; Beličev Petar
  • 期刊名称:Nuclear Technology and Radiation Protection
  • 印刷版ISSN:1451-3994
  • 出版年度:2012
  • 卷号:27
  • 期号:3
  • 页码:297-304
  • DOI:10.2298/NTRP1203297S
  • 出版社:VINČA Institute of Nuclear Sciences
  • 摘要:

    Successful radiotherapy treatment depends on the absorbed dose evaluation and the possibility to define metrological characteristics of the therapy beam. Radiotherapy requires tumor dose delivery with expanded uncertainty less than ±5 %. It is particularly important to reduce uncertainty during therapy beam calibration as well as to apply all necessary ionization chamber correction factors. Absorbed dose to water was determined using ionometric method. Calibration was performed in reference cobalt beam. Combined standard uncertainty of the calculated absorbed dose to water in 65 MeV proton beam was ±1.97% while the obtained expanded uncertainty of absorbed dose for the same beam quality was ±5.02%. The uncertainty estimation method has been developed within the project TESLA.

  • 关键词:protons; absorbed dose; therapy; uncertainty
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