摘要:This study was carried out to analyze the effect of sublethal and lethal concentration (0.1mg/l, 0.2mg/l, 0.4mg/l, 0.8mg/l and 1.6mg/l) of Mospilan 20SG insecticide upon some physiological parameters (oxygen consumption, breathing frequency) and gill histopathology on prussian carp (Carassius auratus gibelio Bloch). The acute and subacute toxicity of this insecticide was evaluated in glass aquaria under semi-static conditions. Mospilan 20SG, is a systemic insecticide from the neonicotinoidic group of products with acetamiprid as active substance. It is used routinely in agriculture and domestic areas against a wide range of insect pests. The toxic has changed the fish respiratory rhythm and oxygen consumption in all investigated concentration after seven days of exposure. We observed that the insecticide had an inhibiting effect on oxygen consumption for the prussian carp. We also reported sign of poisoning in fish, witch included loss of schooling behavior, swimming near the water surface, hyperactivity, erratic swimming, seizures, loss of buoyancy, increased cough rate, increased gill mucus secretions, flaring of the gill arches, head shaking and listlessness before death. The gills showed marked alterations in the epithelia in response to Mospilan 20SG (0.1mg/l water) treatment: dilation of the marginal channel, hyperplasia of the epithelial cells and lifting of the lamellar epithelium, lamellar aneurysm and epithelium rupture with hemorrhage.