摘要：Dermatoglyphics, the patterns of ridges on the skin of the fingertips, palms, and soles, are mostly related with inheritance. The purpose of this study is to verify the possibility that dermatoglyphics are helpful for the diagnosis of sickle cell anemia. The differences of qualitative (finger ball patterns, palmar creases, and location of axial triradii) data were tested for their significance using the chi-square test, and quantitative (ridge counts and palmar atd angle and interradial a-b ridge count) data analysis was done using F-Test (ANOVA). The study included 59 sickle cell anaemia patients (25 females and 34 males), sixty cases of carriers of sickle cell (30 males and 30 females) and sixty age matched controls (30 males and 30 females). Comparisons across the three groups of patients (HB SS, HB AS and HB AA) were done. In this study, the ulnar loop pattern had the highest frequency in both sexes of HB AS and HB AA individuals, whereas it was noticeable that males of sickle cell disease had a higher percentage (49.41%) of the whorl pattern when compared to females (25.6%). A significant increase in the Sydney crease was observed in the males of sickle cell disease patients. In the present study TFRC and atd angles showed significant increase in patients which can conclude that sickle-cell anemia has dermatoglyphic correlation and could be considered as marker for male as well as female patients as the diagnostic tool in linking sickle cell anemia to dermatoglyphics.
