摘要:Astaxanthin is a main carotenoid pigment. Fed-batch fermentation bioprocesses of astaxanthin in 2.0 M3 fermentor have been investigated. Moreover, pH shift control was employed in fed-batch fermentation at 2.0 M3 scale. The results of astaxanthin fermentation showed that the fed-batch fermentation with pH shift strategy was the best among all the experiments, and the maximum astaxanthin concentration of 39.47 mg/L was achieved at 132 h.