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  • 标题:Common criteria among States for storageand use of dried blood spot specimensafter newborn screening
  • 本地全文:下载
  • 作者:Carlo Petrini ; Antonella Olivieri ; Carlo Corbetta
  • 期刊名称:Annali dell'Istituto Superiore di Sanita
  • 印刷版ISSN:0021-2571
  • 出版年度:2012
  • 卷号:48
  • 期号:02
  • 页码:119-121
  • DOI:10.4415/ANN_12_02_03
  • 出版社:Editrice Kurtis Srl
  • 摘要:Biological samples collected in biobanks are a resource with significant research potential. The Italian Joint Group CNB - CNBBSV (National Committee of Bioethics - National Committee for Biosecurity, Biotechnologies and Life Sciences) published a document reporting recommendations on storage and use of dried blood spot (DBS) and on the development of a National Network of Regional Newborn Screening Repositories for collection of residual DBS. Several ethical questions (about consent, possible use of genetic information, unanticipated possible usages for research purposes) rise from residual newborn screening specimens collections. Moreover, legal and ethical controversies are accentuated by the conflicts between the interests of sample donors, biobank holders, researchers and the public. To overcome these difficulties the identification of a few criteria for storage and research usage of DBS is crucial.
  • 关键词:dried blood spot (DBS) storage; neonatal screening; ethics.
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