期刊名称：Electronic Proceedings in Theoretical Computer Science
电子版ISSN：2075-2180
出版年度：2009
卷号：11
页码：35-49
DOI：10.4204/EPTCS.11.3
出版社：Open Publishing Association
摘要：We present the MIM calculus, a modeling formalism with a strong biological basis, which provides biologically-meaningful operators for representing the interaction capabilities of molecular species. The operators of the calculus are inspired by the reaction symbols used in Molecular Interaction Maps (MIMs), a diagrammatic notation used by biologists. Models of the calculus can be easily derived from MIM diagrams, for which an unambiguous and executable interpretation is thus obtained. We give a formal definition of the syntax and semantics of the MIM calculus, and we study properties of the formalism. A case study is also presented to show the use of the calculus for modeling biomolecular networks.
