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  • 标题:Multiscale Bone Remodelling with Spatial P Systems
  • 本地全文:下载
  • 作者:Diletta Cacciagrano ; Flavio Corradini ; Emanuela Merelli
  • 期刊名称:Electronic Proceedings in Theoretical Computer Science
  • 电子版ISSN:2075-2180
  • 出版年度:2010
  • 卷号:40
  • 页码:70-84
  • DOI:10.4204/EPTCS.40.6
  • 出版社:Open Publishing Association
  • 摘要:Many biological phenomena are inherently multiscale, i.e. they are characterized by interactions involving different spatial and temporal scales simultaneously. Though several approaches have been proposed to provide "multilayer" models, only Complex Automata, derived from Cellular Automata, naturally embed spatial information and realize multiscaling with well-established inter-scale integration schemas. Spatial P systems, a variant of P systems in which a more geometric concept of space has been added, have several characteristics in common with Cellular Automata. We propose such a formalism as a basis to rephrase the Complex Automata multiscaling approach and, in this perspective, provide a 2-scale Spatial P system describing bone remodelling. The proposed model not only results to be highly faithful and expressive in a multiscale scenario, but also highlights the need of a deep and formal expressiveness study involving Complex Automata, Spatial P systems and other promising multiscale approaches, such as our shape-based one already resulted to be highly faithful.
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