The aim of this article is to present the main directions of changes in the spatial-demographic settlements organization of Zaplanje, which, due to rapid demographic recession since the 60s of the 20th century, is the strongest depopulation area with the oldest population in Serbia. This research aims is to determine the main types of changes in demographic development of the settlements and indirectly reveals key issues of the sustainable development of Zaplanje settlements and revitalization of villages. [Projekat Ministarstva nauke Republike Srbije, br. 176017]