This paper analyzes thermal environment condition in Banat on the basis eighteen year long data series in the period 1992-2008. Two thermal indexes (TI), suggested by World meteorological organization, are used, heat index and wind chill index. Analysis shows that mean annual TI were lower than mean annual air temperatures that indicate considerable influence of wind on feeling temperatures in Banat. Analysis also shows that TI increased at rate 0.7°C per decade that is likely to be due to a rise in air temperature under global warming and urban development. Besides TI growth, increasing trend of frequency of TI in heat stress categories is found (1.63 days per years). Frequency of TI in cold stress categories shows a trend of a decrease (0.26 days per years). Unfavorable thermal conditions during the summer have Zrenjanin, while during the winter time Kikinda.