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  • 标题:THE METABOLISM OF DRUGS / TOXICS IN THE BODY.CASE STUDY: BZP
  • 本地全文:下载
  • 作者:Gheorghita ZBANCIOC ; Costel MOLDOVEANU ; Robert GRADINARU
  • 期刊名称:International Journal of Criminal Investigation
  • 电子版ISSN:2247-0271
  • 出版年度:2011
  • 卷号:1
  • 期号:1
  • 页码:17-24
  • 出版社:AIT Laboratories
  • 摘要:In this paper was presented a way of identifying and determining the structure of 1-benzylpiperazine (BZP) from biological samples based on its metabolic products. The structure identification of each metabolite of BZP (PYP, BZA and BA) has been done by analyzing the mass spectra and fragmentation reactions of all these compounds. A retrosynthetic analysis for reconstruction of BZP molecule from its metabolic fragments, is presented. This method is general and could be used, in principle, for all drugs and toxics.
  • 关键词:benzylpiperazine; mass spectra; forensic; morphino-mimetic
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