期刊名称：International Journal of Collaborative Research on Internal Medicine & Public Health
电子版ISSN：1840-4529
出版年度：2012
卷号：4
期号：10
出版社：DRUNPP Sarajevo
摘要：Introduction/Background: Increasing blood serum CRP level (C - reactive protein) in schizophrenic patients has been shown in recent studies and there have more emphasis on inflammatory aspects of schizophrenic disease. Aim & Objective: In current study, the purpose is to find and show the relationship between cognitive deficits in schizophrenic patients with blood serum CRP level. Methods/Study: The statistical community, including patients with schizophrenia in the age range 18 to 65 years admitted to the Razi hospital in their diagnosis by an expert-based psychiatric diagnostic criterion (DSM-IV-TR) is definitive. Exclusion criteria for patients from the study is: 1) primary diagnosis of drug dependence, or sign of taking them, 2) a history of mental retardation, 3) having any history of clinical disorders that effect on cognitive vision, such as epilepsy and seizures, history of encephalitis or trauma (physical damage) to the skull or any central nervous system disorder. Using MMSE (Mini-Mental State Examination Questionnaire), 75 severely impaired cognitive patients were randomly selected. Also, in order to determine CRP serum, sample blood for fasting through immunoassay was measured, then through descriptive and inferential statistics, also showed and analyzed. In order to analyze the data in the description of frequency, percentage, mean and standard deviation, and in statistical inference of correlation, regression, ANOVA and t-test was used
关键词：Blood; high CRP serum; low CRP serum; cognitive deficit; schizophrenia
