In this study, the amount of Fe, Zn, Pb, Cu, Mn and Ni accumulated in soil and in different part of water melon irrigated with Tigris River polluted by Ergani-Maden Copper Factory wastes have been detennined an compared with those uneffected by this pollution growing in the neighborhood of Kabaklı Pond. The obtained results show that the amounts of heavy metals in soil and different parts of water melon irrigated with Tigris River are higher than those in the soil and plants not irrigated with this river.