In this study, extracts of Tnchoholoma terreum (Fr.) Kummer were prepared with ethyl acetate, acelone, chloroform and ethanol and antimicrobial activities of these extracts were examined on test microorganisms Aeromonas hydrophila ATCC 7966. Listeria monocytogenes ATCC 19117, Escherichia coli ATCC 11230, Enterobacter aerogenes ATCC 13048. Corynebacterium xerosis CCM 2824, Corynebacterium glutamicum ATCC 13022, Proteus vulgaris ATCC 8427, Serratia marcescens NRRL 3284. Bacillus cereus ATCC 7064, Bacillus subtilis ATCC 6633, Bacillus brevis ATCC 9999. Bacillus sphaericus, Mycobacterium smegmatis CCM 2067, Sarcina lutea, Micrococcus lutcus LA 2971, Staphylococcus aureus ATCC 6538P, Stapylococcus epidermidir NRRL B-4877, Alcaligenes faecalis CCM 3763, Alcaligenes eutrophus, Salmonella parathyphi B, Salmonella thyphi ATCC 19430. Salmonella thyphimurium CCM 5445, Klebsiella pneumoniae UC57. Micrococcus roseus, Mirococcus flavus ATCC 14452, Citrobacter freundii ATCC 8090, Bordatella bronchiseptica ATCC 4617, Erwinia amylovora, Pseudomonas extorquens. Pseudomonas fluorescens, Pseudomonas aeruginosa ATCC 27853, Pseudomonas putida, Xanthomonas campestris, Kluyveromyces fragilis NRRL 2415, Candida albicans ATCC 10231, Candida utilis LA 991, Hansenula sp., Rhodotorula rubra, Debaryomyces sp., Saccharomyces cerevisiae ATCC 9763. Schizosaccharomyces sp.. Torulopsis sp. and Torula sp. by dise diffusion methods. As a results of study, we have found that Tricholoma terreum (Fr.) Kummer extracts revealed antimicrobial activity against some Gram (+) and (-) bacleria but it had no antagonistic effect against yeasts used in this study.