期刊名称：Aktuelnosti iz Neurologije, Psihijatrije i Graničnih Područja
印刷版ISSN：0354-2726
出版年度：2002
卷号：X
期号：1-2
页码：36-44
出版社：Clinical Center of Vojvodina
摘要：Epilepsy in elderly has its own characteristics related to the etiology, types of seizures, and the therapeutic approach. There is a co-morbidity with various somatic diseases. The results of recent studies indicate that the anticonvulsant activity differs in some respects in old age. This study was done to evaluate the incidence of risk factors and etiology, to determine the type of seizures, effects of AE, and EEG findings. The prospective study was undertaken during the period of three years (1998 – 2000) The subjects of the study were 57 newly revealed patients with epilepsy over the age of 55 (37 male and 20 female). The analysis of patients included physical and neurological examinations, EEG, CT or MR, MRA, Doppler ultrasonography, detailed cardiological evaluation and laboratory screenings (lipidograph, antiphosholipid antibody, blood analysis). The average age of patients was 64,2 years (55–84 years) Generalized tonic clonic seizures were the most frequent type - in 26 patients (45,6%), then partial complex seizures and partial seizures with secondary generalization in 8 (14%) patients each. The most common etiological factor of epilepsy in this age was stroke, in 21 patients (36,8%), then alcohol abuse, brain injuries, brain tumors, and brain infections. Abnormal EEG activity was found in a half of the examined patients, and in 2/5 of them specific EEG findings were registrated. Our results show the most frequent causes of epilepsy in elderly to be stroke, brain tumor, brain trauma and brain infection. The most frequent risk factors are hypertension, cardiac disease, hyperlipidemia, and alcohol abuse. EEG analysis is less significant and less specific in elderly than in younger patients
