期刊名称：Aktuelnosti iz Neurologije, Psihijatrije i Graničnih Područja
印刷版ISSN：0354-2726
出版年度：2002
卷号：X
期号：3-4
页码：8-14
出版社：Clinical Center of Vojvodina
摘要：The intracranial haemorrhage syndrome encompasses several clinical entities, of which subarahnoid and intracerebral haemorrhage (SAH and ICH) are the most important with respect to their incidence and importance of prompt recognition and initiation of therapy. The aim of the study was to determine, i.e. confirm the role and importance of risk factors - associated disorders with respect to the outcome and prognosis. The study included 50 patients with ICH, treated conservatively in our hospital. All the patients underwent examinations for the grade of neurological and functional deficit (the Canadian Neurological Scale and the Barthel Index), impairment of consciousness (the Glasgow Coma Score), presence of hypertension (ophtalmoscopy), glycoregulation disturbance (daily glycemia profile), and alcohol habits (daily alcohol intake multiplied by length of alcohol consumption). After the treatment, the assessments of neurological and functional deficits, and impairment of consciousness were repeated. SAH and ICH were confirmed using computer tomography within the first 48 hours after the clinical presentation. Study results were analyzed using parametric statistical methods, and the biserial correlation and linear regression analysis. Risk factors, i.e. associated diseases play an important role in the genesis and development of intracranial haemorrhage. Hypertension is the most readily recognized risk factor, while alcohol abuse represents the most significant predictive indicator for an unfavorable outcome of this syndrome. Association of several risk factors represents a multiple and non-linear increase in the risk of the worst outcomes. It can be concluded that a clearly determined pathogenetic association of risk factors and ICH on one hand, and the knowledge of the key pathophysiological processes in the syndrome on the other, provide new information for developing a multidisciplinary preventive programme for this serious clinical entity
