期刊名称：Aktuelnosti iz Neurologije, Psihijatrije i Graničnih Područja
印刷版ISSN：0354-2726
出版年度：2005
卷号：XIII
期号：1-2
页码：92-96
出版社：Clinical Center of Vojvodina
摘要：Adolescence alone is a period of great challenges, and if accompanied with a neurologic disease, the adolescent's problems will be multiplied. Epilepsy, as a chronic neurologic disease, may have a huge impact on the adolescent's daily life and have far-reaching psychosocial consequences. Due to a limited number of population surveys, the exact prevalence of psychiatric comorbidity in children and adolescents is not known. It has however been estimated that as many as 40-50% of children and adolescents with epilepsy have a kind of psychiatric disturbance. The etiology is multifactorial and involves probably both neurobiological and psychosocial factors. Potential neurobiological determinants include: age of onset, seizure frequency and severity, type of seizure disorder, and type and number of medications used. Potential psychosocial determinants are: poor adjustment to epilepsy, lack of confidence, social withdrawal, stigma, etc. The most common psychiatric disorders among adolescents with epilepsy are depression and anxiety. Despite the high prevalence, they often remain unrecognized and untreated. The first step in the treatment is the choice of antiepileptic medications with positive psychotropic profile. Comprehensive treatment must include psychosocial interventions, supportive family therapy, behavioral therapy, and other treatment modalities. When psychopharmacotherapy is required, the first choice are agents with low seizure potential.
