期刊名称：Aktuelnosti iz Neurologije, Psihijatrije i Graničnih Područja
印刷版ISSN：0354-2726
出版年度：2006
卷号：XIV
期号：1-2
页码：58-64
出版社：Clinical Center of Vojvodina
摘要：Electromyoneurographic studies are crucial in the evaluation of patients with suspected polyneuropathy. Since polyneuropathy can have hundreds of possible causes, the first step in the evaluation of these patients is to reduce the differential diagnosis to the fewest possible causes using thorough history, clinical examination and electrophysiological studies. Nerve conduction studies (neurography) can often be used to differentiate between acquired and hereditary demyelinating polineuropathies where conduction block and time dispersion represent the key finding. Electroneurography and electromyography play an important role in the diagnosis of Guillain Barre syndrome; abnormal findings are found in 50% of patients during the second week and 85% during the third week after the onset of the disease. Chronic inflammatory polyneuropathy (CIDP) is an acquired demyelinating motor and sensory neuropathy believed to be immunologically mediated. Electroneurographic and electromyographic studies show secondary axonal signs. Patients with CIDP have a lower motor neuronal syndrome clinically resembling progressive muscular atrophy (PMA). PMA is a variant of amyotrophic lateral sclerosis, where electrophysiological studies show characteristics of an acquired segmental demyelinating neuropathy with conduction block along motor nerves, similar to CIDP, although sensory fibers can be minimally affected or spared
