期刊名称：Aktuelnosti iz Neurologije, Psihijatrije i Graničnih Područja
印刷版ISSN：0354-2726
出版年度：2006
卷号：XIV
期号：3-4
页码：21-29
出版社：Clinical Center of Vojvodina
摘要：Peripheral neuropathy occurs in patients with rheumatoid arthritis. The aim of this study was to estimate the frequency of peripheral neuropathy, disease activity, and functional disability of patients with rheumatoid arthritis and extra-articular manifestations. Material and methods: The study included 60 patients (48 female and 12 male) with rheumatoid arthritis, mean age 53.92±7.06. The anatomical stage of the disease and the functional class were analyzed according to Steinbrocker`s criteria. The disease activity and functional disability were measured using the Health Assessment Questionnaire (HAQ) score. Results: Extra-articular manifestations wereobserved in 21 patients (35%) - 15 female and 6 male. Carpal tunnel syndrome was found in 8 patients (13.33%), whereas 1 patient (167%) had ulnar nerve syndrome and mononeuritis multiplex. Rheumatoid nodules were found in 6 (10%) patients. Poor functional status was observed in 66.66% of the patients with extra-articular manifestations (HAQ score ≥2). The median HAQ score was 3.09, and the median disease activity score (DAS28 score) was 5.82. Conclusion: More severe functional disability and greater disease activity were found in the patients with rheumatoid arthritis and extra-articular manifestations. The results of the study show a low frequency of peripheral neuropathy registered in patients with rheumatoid arthritis. Electroneurophysiological examination is recommended as a routine diagnostic study of patients with rheumatoid arthritis
关键词：rheumatoid arthritis; extra-articular manifestations; peripheral neuropathy; Health ;Assessment Questionnaire
