期刊名称：Aktuelnosti iz Neurologije, Psihijatrije i Graničnih Područja
印刷版ISSN：0354-2726
出版年度：2011
卷号：XIX
期号：3-4
页码：1-7
出版社：Clinical Center of Vojvodina
摘要：Diabetic amyotrophy is a subacute asymmetric neuropathy with pains, hypotrophy and weakness in the muscles of upper leg and diffi culty walking. Th e goal of our research was to compare effi ciency of in-travenous immunoglobulins, corticosteroids and immunosuppressives within the treatment of 12 patients with the complication of diabetes mellitus. Th e diagnosis was set on the basis of Electromyoneurographical fi ndings and by exclusion of the other forms of neuropathies, and, within the treatment, we applied intrave-nous immunoglobulins in 2 patients; intravenous high-dose pulse corticosteroids in 3 patients, the oral cor-ticosteroids in 5 patients, and immunosuppressives in 2 patients. Th e assessment of muscular strength on lower limbs was realized by Th e Medical Research Council scale, and the function of walking was assessed on the basis of the walking distance (distance in meters that the patient is able to pass before they have to stop due to weakness in legs). Aft er a year from the beginning of treatment, nine patients (75%) had the ex-cellent recovery (regular walking), and 3 patients (25%) had the moderate recovery (moderate weakness in legs, however, they can walk independently). We achieved the best results in the treatment applying intra-venous immunoglobulins and pulse doses of steroids, which is in accordance with results in the majority of the other studies (all 5 patients treated by the stated drugs had excellent recovery), and poorer results by the application of peroral steroid1s and immunosuppressives.
