期刊名称：International Journal of Hybrid Information Technology
印刷版ISSN：1738-9968
出版年度：2012
卷号：5
期号：2
出版社：SERSC
摘要：To illustrate the different kinetics of cellular self-repair mechanism under external perturbations from outer environment, a mathematical model of DNA damage repair process is proposed by using the Kinetic Theory of Active Particles (KTAP) framework. The profile of cellular self-repair process is represented by two sub-populations, each of which is made up of the active particles with different discrete states. The dynamic kinetics of DNA damage generation, repair mRNA transcription, Repair Protein (RP) translation, DSBC synthesis are investigated by the particle interactions between the molecular pairs within DNA and RP sub-systems
关键词：IR; KTAP; Cellular Self-Repair; DNA Damage; Modeling
