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  • 标题:Acute Toxicity and Genotoxic Evaluation of Metlin® and Metlos® (Organic Agave Fructans)
  • 本地全文:下载
  • 作者:M. I. Gracia ; M. M. Tinoco ; H. M. Rivera
  • 期刊名称:Food and Nutrition Sciences
  • 印刷版ISSN:2157-944X
  • 电子版ISSN:2157-9458
  • 出版年度:2013
  • 卷号:4
  • 期号:7A
  • 页码:106-112
  • DOI:10.4236/fns.2013.47A013
  • 出版社:Scientific Research Publishing
  • 摘要:The aim of the study was to contribute to the information on agave soluble fibers since research has been focused on chicory fiber but not in agave products; thus we assess the acute toxicity and genotoxicity of two organic and high purity dietary soluble fibers from agave, Metlin? and Metlos?. We performed an acute toxicity assay in Hsd:ICR mice and Hsd:Wistar rats and an in vivo genotoxic test. Results showed that there are no deaths at any doses or genotoxicity, so it can be concluded that these products are non-toxic, at the administrated doses and none showed a cytotoxic, clastogenic or aneuploidic effect.
  • 关键词:Agave Fructans; Inulin; Fructooligosacharides
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