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  • 标题:Is there any role of glucose-6-phosphate dehydrogenase in obesity induced metabolic disorder
  • 本地全文:下载
  • 作者:Manisha Sankhla ; Keerti Mathur ; Jai Singh Rathor
  • 期刊名称:Health
  • 印刷版ISSN:1949-4998
  • 电子版ISSN:1949-5005
  • 出版年度:2012
  • 卷号:4
  • 期号:12A
  • 页码:1530-1536
  • DOI:10.4236/health.2012.412A219
  • 出版社:Scientific Research Publishing
  • 摘要:The present study was designed to explore the possible mechanism of obesity associated metabolic syndrome. 150 subjects (120 men and 30 women) in the age-group of 17 - 26 years were studied. Body Mass Index and Waist-to-Hip Ratio were taken as a measure of generalized obesity and abdominal adiposity. The serum concentration of glucose-6-phosphate dehydrogenase increased with increasing levels of Body Mass Index and was found to be significant in obese subjects (Body Mass Index ≥ 30.0 kg/m2) and more so in the obese subjects with abdominal adiposity (p = 0.002) as compared to normal-weight subjects. Karl Pearson coefficient of correlation revealed a significant positive correlation of glucose-6-phosphate dehydrogenase with Body Mass Index (r = 0.499; p
  • 关键词:Obesity; Abdominal Adiposity; Oxidative Stress; Glucose-6-Phosphate Dehydrogenase; Adiponectin
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