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  • 标题:Identification of the child with influenza A (H1N1): Clinical criteria versus the rapid influenza A-B test
  • 本地全文:下载
  • 作者:Jesus Reyna-Figueroa ; Karla Maldonado-Silva ; Ana Elena Limon-Rojas
  • 期刊名称:Open Journal of Preventive Medicine
  • 印刷版ISSN:2162-2477
  • 电子版ISSN:2162-2485
  • 出版年度:2012
  • 卷号:2
  • 期号:2
  • 页码:225-228
  • DOI:10.4236/ojpm.2012.22032
  • 出版社:Scientific Research Publishing
  • 摘要:Introduction: During the influenza A (H1N1) pandemic infection, the Ministry of Health in Mexico recommended that it be considered as a suggestive clinical picture in patients with fever, cough and headache. In some places where the resource was available, the rapid seasonal influenza (A-B) test was used as an alternative identification strategy. Methods: From April 2009 to May 2010, patients under 18 years of age with acute respiratory tract symptoms were included in a retrospective study. They underwent the following procedures: 1) application of the clinical criteria recommended by the federal Ministry of Health during the A (H1N1) pandemic; 2) rapid test for seasonal influenza (A-B), and 3) search for the influenza A (H1N1) virus by means of the real time polymerase chain reaction (RT-PCR). The study was approved by the research and ethics committee at the Central South Hospital of the government-owned Mexican Petroleum Company (PEMEX). Results: One hundred and thirty pediatric patients with a median age of eight years and a range between one and 17 years were included. Taking into account the Ministry of Health’s criteria, we found the following: 50% sensitivity, 69% specificity, 80% positive predictive value and 27% negative predictive value versus the rapid test that displayed 82% sensitivity, 70% specificity, 80% positive predictive value and 27% negative predictive value. Conclusions: Clinical criteria display low sensitivity in the infected children studied, whereas the rapid influenza A-B test constitutes a better option to identify these patients.
  • 关键词:Diagnosis; Influenza H1N1; Efficacy; Criteria; Rapid Test
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