摘要：Ob j e c t i v e s: The U.S. E nvironmenta l Protection Agency is working toward gaining a better understanding of the human health impacts of exposure to complex air pollutant mixtures and the key features that drive the toxicity of these mixtures, which can then be used for future scientific and risk assessments.Da t as O u r c e s: A public workshop was held in Chapel Hill, North Carolina, 22–24 February 2011, to discuss scientific issues and data gaps related to adopting multipollutant science and risk assess-ment approaches, with a particular focus on the criteria air pollutants. Expert panelists in the fields of epidemiology, toxicology, and atmospheric and exposure sciences led open discussions to encour-age workshop participants to think broadly about available and emerging scientific evidence related to multipollutant approaches to evaluating the health effects of air pollution.sy n t h e s i s: Although there is clearly a need for novel research and analytical approaches to better characterize the health effects of multipollutant exposures, much progress can be made by using existing scientific information and statistical methods to evaluate the effects of single pollutants in a multipollutant context. This work will have a direct impact on the development of a multipollutant science assessment and a conceptual framework for conducting multipollutant risk assessments.cO n c l u s i O n s: Transitioning to a multi pollutant paradigm can be aided through the adoption of a framework for multi pollutant science and risk assessment that encompasses well-studied and ubi-quitous air pollutants. Successfully advancing methods for conducting these assessments will require collaborative and parallel efforts between the scientific and environmental regulatory and policy communities
关键词：air pollution; exposure; human health; multipollutant; risk assessment
