摘要:a c k g r o u n d: In late October 2003, a series of wildfires exposed urban populations in Southern California to elevated levels of air pollution over several weeks. Previous research suggests that short-term hospital admissions for respiratory outcomes increased specifically as a result of these fires.oB j e c t i v e: We assessed the impact of a wildfire event during pregnancy on birth weight among term infants.Me t h o d s: Using records for singleton term births delivered to mothers residing in California's South Coast Air Basin (SoCAB) during 2001–2005 (n = 886,034), we compared birth weights from pregnancies that took place entirely before or after the wildfire event (n = 747,590) with those where wildfires occurred during the first (n = 60,270), second (n = 39,435), or third (n = 38,739) trimester. The trimester-specific effects of wildfire exposure were estimated using a fixed-effects regression model with several maternal characteristics included as covariates.re s u l t s: Compared with pregnancies before and after the wildfires, mean birth weight was esti-mated to be 7.0 g lower [95% confidence interval (CI): –11.8, –2.2] when the wildfire occurred during the third trimester, 9.7 g lower when it occurred during the second trimester (95% CI: –14.5, –4.8), and 3.3 g lower when it occurred during the first trimester (95% CI: –7.2, 0.6).co n c l u s i o n s: Pregnancy during the 2003 Southern California wildfires was associated with slightly reduced average birth weight among infants exposed in utero. The extent and increasing fre-quency of wildfire events may have implications for infant health and development