The purpose of this study is to investigate the factors perceived to be influential on voluntary turnover among full time doctors working in public sector medical colleges and hospitals. Doctors of public sector medical colleges and hospitals are considered to be backbone of providing public health facilities and medical education in Pakistan. Consequently, hiring and retention of talented faculty members is the main concern for Health Ministry and the Allied Departments. Job dissatisfaction is an important determinant of the turn-over rates. This study explores this relation as well as the antecedents of job satisfaction and turn-over intentions among a sample of 231 Public Sector Doctors. Findings: availability of alternative employment opportunities, absence of distributive justice, autocratic management styles, inadequate salary, un-satisfying nature of work and attitude of the immediate boss were the factors found to be associated with turnover intentions of the doctors of public sector medical colleges and hospitals. The result of this study will contribute to the guide lines for the policy makers for implementation of better human resource policy. Further, comparative research between the private to the public sector health organizations, nationally as well as internationally could provide a more clear picture.