期刊名称：Annals of the University Dunarea de Jos of Galati. Fascicle VI : Food Technology
印刷版ISSN：1843-5157
电子版ISSN：2068-259X
出版年度：2011
卷号：35
期号：2
页码：46-55
出版社：Galati University Press
摘要：Due to the large number of bioactive substances, with low and very low solubility in water, new and improved investigation methods were developed. Researches in this area have shown that lipid systems in lipophilic substances formulation increase their bioavailability and prevent or reduce the toxicological risk because most of the components involved in the formulation are of natural origin, with a structure compatible with biological membranes components. Among the lipid systems used in the leaching, transport and release of lipophilic substances there are: liposomes, solid lipid nanoparticles, double and single emulsions, autoemulsionante and auto-microemulsionante lipid systems. The last are the subject of the present research and meet specialists in concern for the harmonization of cost-benefit-risk in order to improve population health. Curcumin [(1E, 6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione] is a yellow pigment derived from the rhizome of the plant Curcuma Longa with phenol groups and conjugated double bounds which is unstable at light and basic pH, degrading within 30 minutes. The aim of this study is curcumin solubilization used as alimentary dye in automicroemulsionante systems. Dye/oil/surfactant/cosurfactant mixing ratio was made, based on quaternary phase diagrams. Mesofazice structures were revealed by conductivity and viscosimetric analysis. A curcumin solubilization system in aqueous medium was obtained. On the other hand, this paper studies the colour evolution of these automicroemulsionante systems comparing with hexane dye solution. The use of the chromatic attributes L*, a*and b*and L*, C*and hab, suggested by the Commission Internationale de l'Eclairage (CIE) (i.e., the CIELAB system), obtained from direct transmitance measurements, which made it possible to follow the evolution of colour
关键词：self microemulsifying oil formulation; cosolvents; surfactants; ;quaternary phase diagrams ; var currentpos;timer; function initialize() { timer=setInterval("scrollwindow()";10);} function sc(){clearInterval(timer); }function scrollwindow() { currentpos=document.body.scrollTop; window.scroll(0;++currentpos); if (currentpos != document.body.scrollTop) sc();} document.onmousedown=scdocument.ondblclick=initializeR. Cre.u et al. / AUDJG ¨C Food Technology 35(2) 46-55 ;.;47 ;Introduction ;Recently research on the behavior and properties of nanomaterials have found ;numerous applications in food industry (Moraru et. al.; 2003; Moraru et. al.; 2009). ;Thus; more and more published papers have shown the role of food ;nanotechnology in areas such as: food safety and security (Baeumner; 2004); ;sensory analysis and food nanotexture; fortification of some foods with bioactive ;components (McClements et. al.; 2009). ;Taking into account that in the period 2007-2012 the functional foods market ;increased annually by 5.7% (http//www.foodsciencecentral.com); one of the most ;important application of food nanotechnology is to design new functional foods; ;contributing in this way to the increase of consumers' health. ;A major research activity is the use of plant components (phytochemicals) as food ;supplements or as support for the fortified foods. Due to poor solubility in water ;and even oil; these phytochemicals have low bioavailability and present difficulty ;to be included in food. Therefore; the research in recent years was oriented towards ;using different methods and techniques of biocomponents encapsulation. Thus; the ;systems have achieved high nutritional capacity. One of the solubilization methods ;of the phytochemicals is their inclusion in nanoemulsions. ;Nanoemulsions; known as microemulsions; are liquid systems; stable ;thermodynamically; transparent; with low viscosity and dispersed phase droplets ;between 50-100 nm.;Due to the small size of droplets; the solubilised components can be transported ;easily by cell membrane causing an increase of their concentration in the blood.;Studies have shown that the use of lipid systems in lipophilic substances ;solubilisation increases their bioavailability and prevents or reduces the ;toxicological risk because most of the components involved in formulation are of ;natural origin; with a structure compatible with the components of biological ;membranes. Among the lipid systems used in solubilisation; transport and release ;of lipophilic substances are mentioned: liposomes; solid lipid nanoparticles (SLN); ;single and double emulsions; autoemulsified (SEOF) and automicroemulsionante ;(SMEOF) lipid systems. These last ones make the subject of some recent scientific ;researches and subscribe to specialists concern for cost-advantage-risk equilibrium ;in order to increase the population health (Pegg and Shahidi; 2007). ;The use of autoemulsified and automicroemulsionante lipid systems in ;solubilisation of lipophilic substances has several advantages; such as:;- ;they have a high solubilization capacity and dispersion of active principles; ;- ;autoemulsification and automicroemulsification are spontaneous processes ;occurring at ambient temperature; ;- ;it offers the possibility of system sterilization by filtration;- ;it offers the possibility of active substances protection against the attack of ;biological liquids. ;However; a recent research (Pegg and Shahidi; 2007) in the field of emulsified ;lipid systems emphasizes some restrictions on:
