Present paper present an approach of the Research-Development and Innovation System (RDI) in Europe during the last decade. After a short introduction is presented the European Union formation. Research, development and innovation (RDI) has been studied and analyzed since 2001 by the European Innovation Scoreboard (EIS). Will be presented in the present paper a summary of all the materials from EIS 2001 till IUS 2011. Study concerning RDI system in Europe was done from innobarometers from 2001 till 2010. EIS2007 presents for the first time the European innovation leaders. EIS presents innovative performance of Member States based on annual statistical data collected from national statistical sources of each member country of the European Union through the Community Innovation Survey by using Document Analysis on Innovation Community. Were taken into account, after this short presentation, the relevant composite indicators for European Union for the last decade to analyze the Research-Development and Innovation System in Europe. IUS2011 distinguish between three main types of innovation indicators. The main input factors in the analysis of external innovation performance of firms covers 3 dimensions of innovation. These indicators, based on the IUS2011contain as follows: Human Resources with the evolution of new doctorate graduates, population completed tertiary education, youth with upper secondary level education, Research Systems , Finance and Support. All of these indicators belongs to the category of Enablers. Another indicators studied in the present paper are Firm activities, Linkages & entrepreneurship Intellectual Assets.From the category of Outputs there are Innovators and Economic effects. The composite indicators for EU Research Development and Innovation System were study for the period 2006-2011. Samples data were took from Pro Inno Europe database for simulations in August 2012.