The objective of our research was to find out what is the relation between the level of alcohol consumption and the meaning of life experience in the whole life context among chosen patients at the Mental Hospital Kroměříž, Department 20. For this purpose, we made qualitative analyses of half-structured interviews of six respondents and used the data gained by numerical assessment scales and standardized diagnostic methods of Existential scale and the AUDIT questionnaire. We found out that all respondents perceive values as important in their lives (for example different forms of relationships between people, meaning of work or helping others). Generally, the respondents perceive their lives as meaningful and replenishing as other people. On the other hand, all respondents described inner vacancy and feeling of meaninglessness as a result of high level (as they felt it) alcohol consumption. Two respondents stated that a small amount of alcohol helped them feel life more meaningful. In conclusion we can state that most respondents agreed in a statement in half-structured interview, a self-assessment at the numeric assessment scale and statements captured by standardized diagnostic methods of Existential scale and the AUDIT questionnaire.