摘要：The present study aimed at determining and comparing antimicrobial and radical scavenging activity of leaf and bark extract of Pimenta dioica (Linn.) Merill (Myrtaceae). Antibacterial activity of extracts was evaluated against six bacteria and two fungi by agar well diffusion assay. Radical scavenging effect of extracts was determined by DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging assay. Leaf extract was more effective than bark extract against test microbes and the inhibitory effect was dose dependent. Salmonella typhi and Crypotococcus neoformans were highly sensitive to extracts among bacteria and fungi respectively. Extracts have shown dose dependent scavenging of DPPH free radicals. Leaf extract scavenged DPPH radicals more efficiently than bark extract. The bioactivities of leaf and bark extracts observed in this study could be attributed to the presence of bioactive components in the extracts. The plant can be a potent candidate for the development of agents active against pathogens and oxidative stress.
关键词：pimenta dioica;antimicrobial;agar well diffusion;antioxidant; dpph
