期刊名称：Journal of Materials and Environmental Science
印刷版ISSN：2028-2508
出版年度：2013
卷号：4
期号：6
页码：1066-1071
出版社：University of Mohammed Premier Oujda
摘要：The aim of this work was to investigate the antibacterial activity of essential oil and some extracts of Cistus ladaniferus collected from Oulmes in Morocco against Gram-positive and Gram-negative bacteria. The antibacterial activity was determined by agar diffusion method and the determination of minimum inhibitory concentration (MIC) was done by microtitration technique. The result showed that the essential oil was active against Gram-positive more than Gram-negative bacteria, the essential oil had strong antibacterial activity against Staphylococcus aureus (zone of inhibition of growth is 27 mm) with MIC of 250 μg/ml and Yersinia enterocolitica (zone of inhibition of growth is 25 mm) with MIC of 62,5 μg/μl. Methanolic and aqueous extracts had strong antibacterial activity; the maximum zone of inhibition was noted for methanolic extract against Staphylococcus epidermis (zone of inhibition of growth is 23 mm) and for aqueous extract against Staphylococcus epidermis (zone of inhibition of growth is 20 mm), Staphylococcus aureus (zone of inhibition of growth is 20 mm) and Acinetobacter baumannii (zone of inhibition of growth is 20 mm). The extracts obtained with dichloromethane, ethyl acetate and hexane inhibited some bacteria and the zone of inhibition of growth were respectively 16 mm, 12 mm and 12 mm against Staphylococcus aureus, 13 mm, 11 mm and 8 mm respectively against Yersinia enterocolitica. The results indicate that Cistus ladaniferus can be used for the treatment of various infections and for the development of new antibacterial agents
