标题：Retrospective analysis of pathogens isolated in urinary cultures taken from patients hospitalized at the Department of Nephrology in 2010 and their antimicrobial resistance
摘要：Urinary tract infections ( UTIs) are ones of the most common clinical type of infectious diseases among patients treated in hospitals, constituting about 40-50% of all infections among inpatient adults. Knowledge about microorganisms causing UTIs among hospitalized patients and their antibiotic sensitivity is essential to order effective antibacterial therapy.Aim. The purpose of the study was to indentify microorganisms, that were isolated in urinary samples taken from patients hospitalized in Nephrology Department in 2010 and to assess their antimicrobial resistance in vitro.Material and methods. The 539 examined urinary samples were taken from patients hospitalized in Nephrology Department in Lublin in 2010. The urinary samples were analyzed with Vitek 2 Compact device of BioMeriux.Results. From 539 urinary samples taken from patients hospitalized in Nephrology Department in 2010, 226 (41.9%)were positive. Among Gram negative bacteria Escherichia coli dominated – 40.7%, subsequently strains of Enterobacter cloacae – 6.5%, Klebsiella pneumoniae ssp pneumoniae – 6.5%, Proteus mirabilis – 6.5%, Pseudomonas aeruginosa – 5.2% and other Gram negative bacteria made up totally 11.3% of isolated strains. Gram positive bacteria Enterococcus faecalis were cultured in 7.3% of urinary samples and other Gram positive bacteria constituted totally 12.4 %.Conclusions. The examination of isolated microorganisms indicates rising amount of untypical, multiantimicrobial resistant Gram negative bacteria in pathogenesis of complicated UTIs. Gram positive bacteria cause big therapeutic problem with restricted therapeutic options bring out by rapid development of multidrug resistance. In case of UTI suspicion in inpatient person, it is difficult to predict pathogen and its antimicrobial resistance, therefore urinary culture is essential to order effective treatment. As a result of necessity of using more and more expensive , new antibiotics in treatment of UTIs, it seems to be indispensable to value again the procedure of treatment of UTIs of hospitalized patients, because it is underestimated and doesn’t cover rising costs of therapy
关键词：urinary tract infection; antimicrobial resistance; inpatient UTIs; infekcja dróg moczowych; antybiotykooporność; wewnątrzszpitalne ZUM
