Introduction. Malnutrition is postulated as an important clinical problem in patients with end-stage renal disease (ESRD) undergoing hemodialysis. Nutrition disorders effect poor quality of life, physical, emotional, and social problems in ESRD patients. Malnutrition is a reason of B-, and T-cells immunodeficiency disturbances, inflammation complications, longer hospitalization, and higher mortality in dialysis patients.
Aim. The purpose of this study was to evaluate the correlation between biochemical and clinical parameters of ESRD patients with parameters of nutrition.
Methods. We studied the relationship between red-blood cells serum parameters, dialysis adequacy and blood pressure monitoring, and nutrition status from the other hand, in 69 dialysis patients (30 female, 39 male) treated in Gambro Healthcare Dialysis Center.
Results. The mean duration time on dialysis was 51,50±52,62 months. The mean observed value of target weight was of 68,23±915,27 kg (range from 42,5- to 107,5 kg). We observed serum albumin level less than 3,0g/dl in 8.7 % of patients (severe malnourished group) and nPCR index less than 0,8 g/kf body weight/24 hours in 14.5% treated patients population. The significant correlation between BMI and Kt/V (R=-0,29 p=0,01), but not with serum albumin level has been observed. We observed also significant correlation between serum albumin and hemoglobin concentration (R=0,25 p=0,034). The MAP higher than 100 mmHg we observed in 26,1% of HD patients.
Conclusion. The monitoring of nutrition parameters should be recommended in daily dialysis practice in relation to blood pressure control, dialysis adequacy and red blood cell monitoring in ESRD patients treated on hemodialysis.