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  • 标题:Phytochemical Screening of Ayer Hitam Forest Reserve : Isolation of Ariskanin-A from Thottea corymbosa (Griff.) Ding Hou (Aristolochiaceae)
  • 本地全文:下载
  • 作者:Nik Idris Yusoff ; Siti Zaiton Mat So'ad ; Ujang Suki
  • 期刊名称:Pertanika Journal of Social Sciences & Humanities
  • 印刷版ISSN:0128-7702
  • 电子版ISSN:2231-8534
  • 出版年度:2001
  • 卷号:24
  • 期号:1
  • 出版社:Universiti Putra Malaysia
  • 摘要:During a phytochemical screening of higher plants at Ayer Hitam Forest Reserve, Puchong, Selangor, we collected a large amount of sample of Thottea corymbosa roots for further investigation of its bioactive constituents. The plant is a shrub commonly used in herbal medicine and could easily be found along the open forest trails. The roots of the collected sample were consecutively extracted with petroleum-ether, chloroform and methanol followed by separation of the chloroform fraction by column chromatography and preparative thin-layer chromatography. In this study we reported the isolation of an aristolactam, Ariskanin-A with a toxicity value of LC50 <200 ppm in Brine-Shrimp lethality Bioassay based on spectroscopic data and comparison with literature.
  • 关键词:Thottea corymbosa; Aristolochiaceae; Ariskanin-A; aristolochic acid; herbal medicine.
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