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  • 标题:Development of Bioaffinity Chromatography for Uricase Purification
  • 本地全文:下载
  • 作者:A. B. Salleh
  • 期刊名称:Pertanika Journal of Social Sciences & Humanities
  • 印刷版ISSN:0128-7702
  • 电子版ISSN:2231-8534
  • 出版年度:1980
  • 卷号:3
  • 期号:2
  • 出版社:Universiti Putra Malaysia
  • 摘要:The uricase inhibitors urate, xanthine, oxonate and cyanurate were tried as ligands, for preparing bioaffinity support for chromatographic separation of uricase. Only derivatised purines showed inhibitory properties, whereas derivatised s-triazines seemed to lose their absorptive capacity. Chromatographic separation on a bioaffinity support produced higher yield and better purification of uricase than conventional chromatographic technique.
  • 关键词:uricase; affinity chromatography
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