期刊名称:Pertanika Journal of Social Sciences & Humanities
印刷版ISSN:0128-7702
电子版ISSN:2231-8534
出版年度:1980
卷号:3
期号:2
出版社:Universiti Putra Malaysia
摘要:The uricase inhibitors urate, xanthine, oxonate and cyanurate were tried as ligands, for preparing bioaffinity support for chromatographic separation of uricase. Only derivatised purines showed inhibitory properties, whereas derivatised s-triazines seemed to lose their absorptive capacity. Chromatographic separation on a bioaffinity support produced higher yield and better purification of uricase than conventional chromatographic technique.