SIRT1 is the mammalian ortholog of silent information regulator 2 (Sir2) found in Saccharomyces cerevisiae and functions as a NAD⁺-dependent deacetylase. SIRT1 appears to promote healthy aging and is implicated in the prevention of many age-related pathologies [1]. At the cellular level, SIRT1 controls lipid and glucose homeostasis, DNA repair and apoptosis, circadian clocks, inflammation and mitochondrial biogenesis. The biological effects of SIRT1 are mediated by its ability to deacetylate several key transcription factors such as Peroxisome proliferator-activated receptor-ϒ coactivator 1 alpha (PGC-1α), p53, and FOXO proteins [2].